Method for treatment of airway stricture or stenosis
AssigneeAiriver Medical, Inc.
InventorLixiao Wang
Life of this patent
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Abstract
A method of treating a recurring airway stricture or stenosis in a body lumen includes inserting a scope and a drug-coated balloon catheter into a target site comprising the recurring airway stricture or stenosis in the body lumen. The method includes inflating the balloon to an inflation diameter such that the coating contacts an interior of the body lumen at the target site. The method includes deflating the balloon and withdrawing the scope and the balloon catheter from the target site.
Claims19
A method of treatment of a recurring airway stricture or stenosis in an airway body lumen, the method comprising:
- inserting a scope and a balloon catheter into a target site at the recurring airway stricture or stenosis in the airway body lumen, wherein the balloon catheter comprises
- an elongated balloon, and
- a coating layer overlying an exterior surface of the balloon, wherein the coating layer comprises one or more additives and an initial drug load of a therapeutic agent chosen from paclitaxel, docetaxel, taxol, rapamycin, sirolimus, zotarolimus, everolimus, tacrolimus, an analogue thereof, and a combination thereof;
- inflating the balloon to an inflation diameter such that the coating contacts an interior of the body lumen at the target site;
- deflating the balloon;
- and
- withdrawing the scope and the balloon catheter from the target site;
- wherein the airway body lumen comprises supraglottis, glottis, subglottis, mainstem bronchus, bronchus intermedius, lobar bronchus, or a combination thereof.
A method of treatment of a recurring airway stricture or stenosis in an airway body lumen, the method comprising:
- inserting a scope and a balloon catheter into a target site at the recurring airway stricture or stenosis in the airway body lumen, wherein the balloon catheter comprises
- an elongated balloon, and
- a coating layer overlying an exterior surface of the balloon, wherein the coating layer comprises one or more additives and an initial drug load of a therapeutic agent chosen from paclitaxel, docetaxel, taxol, rapamycin, sirolimus, zotarolimus, everolimus, tacrolimus, an analogue thereof, and a combination thereof;
- inflating the balloon to an inflation diameter such that the coating contacts an interior of the body lumen at the target site;
- deflating the balloon;
- and
- withdrawing the scope and the balloon catheter from the target site;
- wherein the recurring airway stricture or stenosis is a stricture or stenosis induced by eosinophils, IL-4, IL-5, IL-6, IL-13, IL-23, ILC2, goblet cells, cystic fibrosis, or a combination thereof.
Dependencies are inferred from the claim text.