Methods employing gaseous nitric oxide for inhibiting tumor growth
AssigneeBeyond Air, Inc.
InventorsHila Confino, Steven A. Lisi, Rinat Kalaora, Amir Avniel
Life of this patent
Estimating the term…
Abstract
Methods of inhibiting growth of cells or tissue of a primary and/or secondary tumor, and/or of stimulating an immunological response to the tumor, in a subject in need thereof, and systems for performing same, are provided. The methods employ local administration of a gas, such as gaseous nitric oxide, typically at a high dose. Immune cells obtained upon treating a tumor with gaseous nitric oxide, either in vivo or ex vivo, and methods employing same are also provided.
Claims17
A method of inhibiting growth of cells or tissue of a primary and/or secondary tumor in a subject in need thereof, the method comprising locally administering to the tumor gaseous nitric oxide (gNO) at a dose of from about 1,000 ppm to about 1,000,000 ppm for a time period of from about 1 second to about 60 minutes at a volumetric flow of from about 0.00001 LPM to about 1 LPM, wherein locally administering said gNO is by intratumoral injection.
Dependencies are inferred from the claim text.