Bone graft composition
AssigneeSurGen Tec, LLC
InventorsTravis Greenhalgh, Andrew Shoup
Life of this patent
Estimating the term…
Abstract
A particle comprising hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, and/or bioactive glass is provided. The particle can be useful in bone graft compositions further comprising a carrier. The composition can include a quadphasic particle having hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, bioactive glass, and a carrier. The particle can have a size in the range of 50 microns to 2.5 mm. A method of repairing a bone defect is also provided. The method can include a step of applying the bone graft composition to a subject having the bone defect, such as a spinal bone defect. The subject receiving the bone graft composition can be a mammal, namely a human, pet, or domestic animal.
Claims39
A sintered particle comprising one or more particles each of hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, and bioactive glass, wherein the one or more particles each of hydroxyapatite β-tricalcium phosphate, α-tricalcium phosphate, and bioactive glass are sintered together to form a unitary particle;
- wherein the particle has a particle size of about 50 microns to about 2.5 mm, and wherein the sintered particle comprises:
- about 40 wt. % to about 60 wt. % hydroxyapatite;
- about 30 wt. % to about 50 wt. % β-tricalcium phosphate;
- about 2.5 wt. % to about 25 wt. % α-tricalcium phosphate;
- and
- about 5 wt. % to about 20 wt. % bioactive glass.
A bone graft composition comprising a plurality of sintered particles wherein each sintered particle comprises one or more particles each of hydroxyapatite, β-tricalcium phosphate, α-tricalcium phosphate, and bioactive glass sintered together to form a unitary particle;
- and a carrier, wherein the unitary particle comprises:
- about 40 wt. % to about 60 wt. % hydroxyapatite;
- about 30 wt. % to about 50 wt. % β-tricalcium phosphate;
- about 2.5 wt. % to about 25 wt. % α-tricalcium phosphate;
- and
- about 5 wt. % to about 20 wt. % bioactive glass.
Dependencies are inferred from the claim text.