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US 12,691,175 B2Granted
Drug transdermal delivery system
AssigneeXiamen University
InventorsMing Chen, Haojie Zhai
Life of this patent
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Abstract
A drug transdermal delivery system comprises sponge spicules and a low-frequency sonophoresis device, the drug transdermal delivery system firstly applies a low-frequency sonophoresis to skin using the low-frequency sonophoresis device, a surface of the skin is then massaged with the sponge spicules.
Claims7
A drug transdermal delivery method, comprising:
- operations of:
- firstly applying a low-frequency sonophoresis to skin, wherein a frequency of the low-frequency sonophoresis is 10-30 kHZ, and a time during which the low-frequency sonophoresis is applied is 2 minutes or less,
- then massaging a surface of the skin with sponge spicules for 2 minutes, wherein a dosage amount of the sponge spicules is 1 mg/cm2 or less, and
- then administering a drug to the surface of the skin;
- or
- operations of:
- firstly applying the low-frequency sonophoresis on the skin, wherein the frequency of the low-frequency sonophoresis is 10-30 kHZ, and the time during which the low-frequency sonophoresis is applied is 2 minutes or less,
- then massaging the surface of the skin using the sponge spicules for 2 minutes, wherein the dosage amount of the sponge spicules is 1 mg/cm2 or less, and
- administering the drug to the surface of the skin at the same time as the surface of the skin is massaged using the sponge spicules.
6 more elements
Dependencies are inferred from the claim text.