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US 12,691,150 B2Granted
Group B adenovirus-containing formulation
AssigneeAkamis Bio Limited
InventorsSimon Alvis, Magdalena Kieltyka
Life of this patent
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Abstract
The present disclosure relates to formulations suitable for the storage of group B adenoviruses, such as Enadenotucirev (EnAd), processes for making the formulations, and use of the formulations in methods of treatment.
Claims15
A liquid formulation suitable for a group B adenovirus, comprising:
- a) a group B adenovirus;
- b) 15 to 25% v/v glycerol;
- c) methionine or arginine;
- and
- d) buffer,
- wherein the pH of the formulation is in the range of 8.0 to 9.6 and wherein the formulation does not comprise a divalent cation.
3 more elements
Dependencies are inferred from the claim text.