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US 12,691,033 B2Granted
Lyophilized cake in straight-walled vial
AssigneeElanco US Inc.
InventorsDonald D. Evans, II, Mayur Patel, Lee J. Stimpson
Life of this patent
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Abstract
A system including a vial and methods of its use to provide a lyophilized cake removable from the vial without cracking or breaking.
Claims19
A straight-walled vial system (10) comprising:
- a straight-walled vial (14);
- and
- a solid lyophilized vaccine composition within the straight-walled vial (14), wherein the solid lyophilized vaccine composition comprises an antigen and a stabilizer, wherein the stabilizer comprises i SGGK3, and
- wherein the solid lyophilized vaccine composition is a cake (20).
1 more element
A method for preparing a solid lyophilized vaccine composition, the method comprising:
- combining an antigen and a stabilizer to obtain a blend, wherein the stabilizer comprises SGGK3;
- filling a straight-walled vial (14) with the blend;
- lyophilizing the blend in the straight-walled vial (14) to form a solid lyophilized vaccine composition;
- and
- removing the solid lyophilized vaccine composition from the straight-walled vial (14).
2 more elements
Dependencies are inferred from the claim text.