A highly charged Nickel ion optical clock including an optical clock system and an FPGA control system, characterized in that the optical clock system includes a cryogenic ion trap system, a highly charged ions source, an ion beamline system, a ultraviolet fluorescence collection system, a laser modulation system, a servo feedback circuit, an optical frequency comb, and clock signal output system, the highly charged ions source outputs a pulsed beam of highly charged Nickel ions to the ion beamline system, the ion beamline system filters out the pulse beam of Ni12+ ions, collimates and decelerates it, and outputs it to the cryogenic ion trap system, the cryogenic ion system prepares and traps Be+ ions, and also traps Ni12+ ions, the laser modulation system outputs a swept laser to the cryogenic ion trap system to excite Ni12+ ions to an excited state, Ni12+ ions transmit external state information to Be+ ions, Be+ ions emit a 313 nm fluorescence signal, and the ultraviolet fluorescence collection system collects the 313 nm fluorescence signal emitted by Be+ ions to obtain the spectral line shape of Ni12+ ion transition and outputs it to the servo feedback circuit, the servo feedback circuit calculates the spectral line center value of Ni12+ ion transition, and the servo feedback circuit outputs an error signal to the laser modulation system based on the spectral line center value, the laser modulation system shifts the output laser frequency according to the error signal, so that the shifted laser frequency locks to the spectral line center value of Ni12+ ion transition, the laser modulation system outputs the locked laser to the optical frequency comb, which in turn generates an optical frequency comb, measure the laser frequency of the locked laser, and the optical frequency comb outputs the measured laser frequency to the FPGA Control system, FPGA control system outputs clock signals to clock signal output system, clock signal output system outputs clock signals, FPGA control system is also connected to the cryogenic ion trap system, ion beamline system, ultraviolet fluorescence collection system, laser modulation system, optical frequency comb, and clock signal output system through timing control signal lines.