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US 12,687,481 B2Granted
Method for characterising biological particles in aerosol form using laser-induced plasma spectrometry and associated system
AssigneesCommissariat A L'energie Atomique Et Aux Energies Alternatives, Centre National De La Recherche Scientifique
InventorsOlivier Sublemontier, Jean-Philippe Renault
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Abstract
The disclosure relates to a method for characterizing biological particles in aerosol form, such as suspended in an ambient gas, by laser-induced breakdown spectrometry and an associated system.
Claims15
A method for characterising biological particles of a size less than or equal to 200 nm as an aerosol by laser-induced breakdown spectrometry, said method comprising the following steps:
- a) sampling ambient gas, which comprises the biological particles sought to be characterised;
- b) generating a jet of said particles (JAB) in a chamber (CH) under vacuum;
- c) emitting a laser beam (FL) in the form of pulses with a repetition frequency comprised between 1 kHz and 1 MHz, and focusing said laser beam in said vacuum chamber (CH), transversely to a propagation direction of the particle jet (JP), to create, in a focal volume (VF), a plasma by the interaction between the laser beam (FL) and at most one individual particle (NP) of the jet, said plasma emitting other particles, characteristics of the interaction between the laser beam and said individual particle of the jet;
- d) collecting said particles emitted from the plasma;
- and
- e) performing a spectrometric analysis of these particles to finally characterise said biological particles.
3 more elements
Dependencies are inferred from the claim text.