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US 12,686,852 B2Granted
Support and system for engineered tissue
AssigneeNovoheart International Limited
InventorsErin G. Roberts, Eugene K. Lee, David D. Tran, Suet Yee Mak, Bernard Fermini, Andy Wong
Life of this patent
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Abstract
The present disclosure relates to tissue supports for use with engineered tissues and organoids, such as cardiac organoid chambers. In an embodiment of the present disclosure, the tissue supports are provided with a fluid-impermeable resilient member that is resiliently deformable during testing by cultured tissues formed on the surface of the tissue support.
Claims13
A tissue support comprising a fluid-impermeable resilient member having an external surface and defining an enclosed volume;
- wherein the external surface of the fluid-impermeable resilient member is resiliently deformable by cultured tissues formed on the external surface of the fluid-impermeable resilient member during testing thereof, and wherein the fluid-impermeable resilient member is retained in place during the testing.
A tissue support comprising:
- a fluid-impermeable resilient member having an external surface and defining an enclosed volume, and a wall of generally consistent thickness between 40-300 μm;
- wherein the external surface of the fluid-impermeable resilient member is resiliently deformable by cultured tissues formed on the external surface of the fluid-impermeable resilient member during testing thereof.
A tissue support comprising:
- a fluid-impermeable resilient member having an external surface and defining an enclosed volume having a loading volume between a range of 300 to 600 μL;
- wherein the external surface of the fluid-impermeable resilient member is resiliently deformable by cultured tissues formed on the external surface of the fluid-impermeable resilient member during testing thereof.
Dependencies are inferred from the claim text.