Multivalent terpene-based bolaamphiphiles for gene delivery

A compound of Formula (I):

• wherein:
• each A is independently selected from:
• each Z is independently —S—R1;
• each R1 is independently selected from:
• each R2 or R3 is independently selected from hydrogen, C1-C6 alkyl, C1-C6 alkenyl, aralkyl, or hydroxyalkyl;
• each R4, R6 or R7 is independently selected from C1-C6 alkyl, C1-C6 alkenyl, or hydroxyalkyl;
• each R5 is hydrogen or C1-C3 alkyl;
• each X is halogen;
• each m is an integer independently selected from 1-10;
• each q is an integer independently selected from 1-200;
• each B is independently selected from:
• wherein each R is independently selected from hydrogen or C1-C6 alkyl;
• and
• C is:
• a. a C2-C100 hydrocarbon chain which can optionally contain one or more S atoms;
• b. CycA-L-CycB, wherein CycA and CycB are each independently a 5-8 membered cycloalkyl chain and L is C1-C3 alkylene;
• c. a polyalkylene oxide or polyalkylene oxide block copolymers of 200-5,000 molecular weight;
• d. an aliphatic or aromatic polyester of 200-5,000 molecular weight;
• or
• e. an aliphatic or aromatic polyurethane of 200-5,000 molecular weight;
• or
• together form:
• wherein each R8 is independently selected from C2-C6 alkyl, aryl,
• and wherein each t is an integer independently selected from 1-10.