Fluid catheter device for recording brain state
AssigneeBiogen MA Inc.
InventorsDaniel J. Abrams, Matias Maturana
Life of this patent
Estimating the term…
Abstract
A device or system for delivering fluid to or removing fluid from a CSF-containing space of a brain and for recording electrical activity from white or grey matter in the brain includes a catheter including a proximal end, a distal end portion, a first lumen extending from the proximal end to the distal end portion, and one or more electrodes positioned relative to the catheter a distance from a distal end of the catheter, such that the one or more electrodes would be placed in contact with white or grey matter of the brain if the distal end of the catheter were positioned in the CSF-containing space. The catheter may include the electrodes or a lead adjacent the catheter may include the electrodes.
Claims33
A device or system for delivering fluid to or removing fluid from a cerebrospinal fluid (CSF)-containing space of a brain and for recording electrical brain state activity from white or grey matter in the brain, the device or system comprising:
- a CSF catheter comprising a proximal end, a distal end portion, and a first lumen extending from the proximal end to the distal end portion;
- and
- a brain lead extending from and coupled to the CSF catheter by a snap fit connector comprising at least one deflectable element configured to resiliently deflect as at least one of the brain lead or the CSF catheter is inserted, the brain lead comprising an electrode positioned a distance from the distal end of the CSF catheter such that the electrode is configured to contact white or grey matter of the brain when the distal end of the CSF catheter is placed in the CSF-containing space;
- signal processing electronics configured to operably couple to the brain lead and to record electrical activity detected by the electrode and to determine a brain state or to predict a future brain state;
- and
- an external apparatus configured to wirelessly receive signals associated with the recorded electrical activity from the signal processing electronics.
A device or system comprising:
- an implantable access port, the access port comprising:
- an opening accessible by a needle when the access port is implanted;
- a first catheter connector;
- a second catheter connector;
- a first fluid flow path extending from the opening to the first catheter connector;
- and
- a second fluid flow path extending from the second catheter connector to the first catheter connector;
- a CSF catheter coupled to, or operably couplable to, the first catheter connector, the CSF catheter comprising a proximal end, a distal end portion, and first and second lumens extending from the proximal end to the distal portion of the CSF catheter;
- a brain lead extending from and coupled to the CSF catheter by a snap fit connector comprising at least one deflectable element configured to resiliently deflect as at least one of the brain lead or the CSF catheter is inserted, the brain lead comprising an electrode configured to detect electrical activity determinative of a brain state or predictive of a future brain state,
- wherein the first lumen is in communication with the first fluid flow path and the second lumen is in communication with the second fluid flow path when the proximal end of the CSF catheter is coupled to the first catheter connector,
- wherein the CSF catheter has a length such that a distal end is configured to extend to a CSF-containing space of a subject when the access port is implanted,
- wherein the electrode is positioned a distance from the distal end of the CSF catheter and configured to be positioned in white or grey matter of a brain of the subject when the access port is implanted and the distal end of the CSF catheter is positioned in the CSF-containing space;
- signal processing electronics configured to operably couple to the brain lead and to record electrical activity detected by the electrode and to determine a brain state or to predict a future brain state;
- and
- an external apparatus configured to wirelessly receive signals associated with the recorded electrical activity from the signal processing electronics.
Dependencies are inferred from the claim text.