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US 12,685,804 B2Granted
Composite materials and methods of making and using the same
AssigneeThe Board of Trustees of the University of Illinois
InventorsBrendan A. C. Harley, Marley J. Dewey, Justine Lee
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Abstract
Composite materials including a macroporous structure having a Voronoi architecture and a microporous biomaterial integrated into the macroporous structure are provided. Methods of making the composite materials and methods of using the materials to treat a bone defect are also provided.
Claims17
A composite material comprising:
- a macroporous structure having a Voronoi architecture, the macroporous structure comprising a deformable mesh comprising a plurality of pores;
- a microporous biomaterial integrated into the macroporous structure;
- and
- wherein the macroporous structure is configured to achieve conformal shape-fitting via the deformable mesh when implanted within a bone defect.
1 more element
A method of treating a bone defect, comprising:
- implanting a composite material comprising a macroporous structure having a Voronoi architecture and a microporous biomaterial integrated into the macroporous structure in a bone defect in a subject, wherein the macroporous structure comprises a deformable mesh comprising a plurality of pores and wherein the deformable mesh allows the macroporous structure to achieve conformal shape-fitting within the bone defect.
Dependencies are inferred from the claim text.