Compositions and methods for treating lung injury
AssigneesUniversity of Maryland, Baltimore, The United States Government as represented by the Department of Veterans Affairs
InventorsJ. Marc Simard, Vladimir Gerzanich, Caron M. Hong
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Abstract
The present invention provides methods of reducing lung injury in a subject in need thereof, comprising administering to the subject an effective amount of an agent that inhibits the activity of SUR1.
Claims10
A method of treating acute lung injury in a human subject in need thereof, comprising administering to the subject an effective amount of an agent that inhibits the activity of SUR1, wherein the agent is glibenclamide, wherein glibenclamide is administered to the subject in an amount of between about 0.5 mg/day to about 10 mg/day, wherein the subject is on a mechanical ventilator.
Dependencies are inferred from the claim text.