Use of 2,3,5-substituted thiophene compound for enhancement of radiotherapy
AssigneePharos Ibio Co., Ltd.
InventorsJeong Hyeok Yoon, Ky Youb Nam
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Abstract
The present disclosure relates to a composition for enhancing radiotherapy, the composition containing a 2,3,5-substituted thiophene compound of Formula 1 or a pharmaceutically acceptable salt thereof. The composition may increase the sensitivity of cancer cells to radiation, and thus may be advantageously used to enhance the effect of radiotherapy. Also provided is a method for anticancer radiotherapy, the method including steps of: administering the composition for enhancing radiotherapy to a subject; and irradiating the subject with radiation. Further provided is a method for enhancing the effect of radiotherapy, the method including a step of administering the composition for enhancing radiotherapy to a subject.
Claims6
A method for enhancing anticancer radiotherapy, the method comprising steps of:
- administering to a subject in need thereof an effective amount of a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof;
- and irradiating the subject with radiation at 3 Gy twice at 7-day intervals, wherein the compound is administrated in combination with the radiation;
A method for enhancing the effect of radiotherapy, the method comprising a step of administering to a subject in need thereof an effective amount of a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, wherein the subject has cancer, and the cancer is colorectal cancer, head and neck cancer or breast cancer:
- wherein the radiotherapy is irradiating the subject with radiation at 3 Gy twice at 7-day intervals, wherein the compound is administered in combination with the radiation.
Dependencies are inferred from the claim text.