Systems and methods for integrated magnetic resonance imaging and magnetic resonance fingerprinting radiomics analysis

A method for generating radiomic feature data from magnetic resonance images and magnetic resonance fingerprinting maps, the method comprising:

• (a) accessing with a computer system, magnetic resonance imaging (MRI) data acquired from a subject with an MRI system;
• (b) accessing with the computer system, magnetic resonance fingerprinting (MRF) data acquired from the subject, wherein the MRF data comprise quantitative parameter maps;
• (c) preprocessing the MRI data and the MRF data with the computer system;
• (d) performing an integrated radiomic analysis on the preprocessed MRI data and the preprocessed MRF data with the computer system to generate output as radiomic feature data, wherein the integrated radiomic analysis extracts radiomic features from coregistered MRI and MRF data within regions-of-interest, where the radiomic features comprise at least shape features, first-order statistical features, and second-order statistical features computed from the quantitative parameter maps of the MRF data;
• and
• (e) generating a report based on the radiomic feature data using the computer system.