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US 12,681,025 B2Granted
Method and kit for monitoring anticoagulant therapy
AssigneeFiix Diagnostics
InventorsPall T. Onundarson, Brynja R. Gudmundsdottir
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Abstract
A method and kit are provided for measuring and monitoring a combined effect of an anticoagulant drug on coagulation factors II and X in a patient taking the anticoagulant drug. The method includes adding one or more coagulation reagents with the factor VII to a test sample and determining blood clotability of the test sample by measuring an influence of factors II and X.
Claims11
A method for measuring and monitoring a combined effect of an anticoagulant drug on coagulation factors II and X in a patient taking the anticoagulant drug, the method comprising:
- obtaining a test sample from the patient;
- mixing factor VII into one or more coagulation reagents that activate factor X through factor VII and bypasses factor IX;
- adding the one or more coagulation reagents with the factor VII to the test sample;
- and
- determining blood clotability of the test sample by measuring an influence of factors II and X.
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