Method and device for processing tissues and cells by rotating microfluidic chips mounted on a support plate
AssigneeSyntr Health Technologies, Inc.
InventorsAhmed Zobi, Adrian Bahani, Justin Stovner, Hugo Salas
Life of this patent
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Abstract
Devices and methods of processing a sample that includes rotating one or more microfluidic chips that are mounted on a support plate. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run bidirectionally through each of the microfluidic chips. Each of the microfluidic chips can include a fluid path comprising a plurality of expansion and compression regions that increase in radius in more than two dimensions. The support plate may be configured to reversibly interact with one or more carriage assemblies, which may be operatively coupled to the support plate.
Claims20
A system for processing biological samples comprising:
- a support plate comprising:
- a central portion configured to reversibly interact with a motor for providing rotational force, and
- at least one lateral arm, wherein each of the at least one lateral arms includes a first opening and at least one securement opening;
- at least one carriage assembly, wherein each of the at least one carriage assemblies is configured to reversibly interact with one of the at least one lateral arms, wherein each of the at least one carriage assemblies comprises:
- a base comprising:
- a top surface comprising at least one circular groove,
- a bottom surface comprising a post configured to extend through the first opening of one of the at least one lateral arms,
- a first arm, and a second arm;
- a spring platform comprising:
- at least one circular groove positioned on a bottom surface of the spring platform,
- a first engagement portion,
- a second engagement portion, and
- wherein the spring platform is positioned adjacent to the top surface of the base,
- at least one spring retained between the base and the spring platform, wherein the at least one spring is secured at a first end in the at least one circular groove of the base and at a top end in the at least one circular groove of the spring platform, wherein the at least one spring is configured to provide an upward force on the spring platform, and
- a securing element configured to secure a chip assembly on the at least one carriage assemblies;
- and wherein each of the at least one carriage assemblies is at least rotatable about 180 degrees.
Dependencies are inferred from the claim text.