Back to results
US 12,679,818 B2Granted
Radioactive halogen labeling precursor compound
AssigneesInstitute of Science Tokyo, Fukushima Medical University, Taiyo Nippon Sanso Corporation
InventorsHiroshi Tanaka, Kazuhiro Takahashi, Miho Suzuki
Life of this patent
Estimating the term…
Abstract
Provided is, as a radioactive halogen labeling precursor compound that is highly reactive and stable, a compound represented by the following general formula (II): wherein R1 and R2 each independently represent an alkyl group having 5 to 20 carbon atoms, X1 and X2 each independently represent a halogen atom, and R3 represents a monovalent group derived from a sugar, or the like.
Claims10
A compound represented by the following general formula (I):
- wherein R1 and R2 each independently represent an alkyl group having 5 to 20 carbon atoms, X1 and X2 each independently represent a halogen atom, and X3 represents a halogen atom.
A compound represented by the following general formula (II):
- wherein R1 and R2 each independently represent an alkyl group having 5 to 20 carbon atoms, X1 and X2 each independently represent a halogen atom, and R3 represents (i) a monovalent group derived from a sugar, which is a monovalent group obtained by removing one hydrogen atom in the sugar;
- (ii) a monovalent group derived from a peptide, which is a monovalent group obtained by removing one hydrogen atom in the peptide;
- or (iii) a group represented by the following general formula (A) or (B):
- wherein L represents a divalent group that functions as a spacer, R4 represents an aryl group optionally substituted with a substituent, a heteroaryl group optionally substituted with a substituent, or an aminocarbonyl group optionally protected by a protective group, and * represents a bonding site.
1 more element
Dependencies are inferred from the claim text.