Method for the preparation of sulfinpyrazone

Abstract

The present disclosure discloses a method for the preparation of sulfinpyrazone, which is produced in two steps with a total yield of 48%, wherein thiophenol as the starting material is electrocatalytically coupled with dichloroethane to obtain 2-chloroethyl phenyl sulfoxide, which then undergoes a substitution reaction with 1,2-diphenyl-3,5-pyrazolidinedione to produce sulfinpyrazone. Compared with the prior art, the present method is characterized by high yield, short steps, less three wastes, good chemical selectivity, no need to use strong bases and oxidants, safe and simple operation, and easy to realize industrial production.

Dependencies are inferred from the claim text.