Droplet generation method, system and application

A droplet generation method, using a droplet generation device and a droplet receiver, wherein, a first liquid is placed in the droplet receiver, the droplet generation device comprises a fluid passage, an accommodating cavity having a volume which is variable and in liquid communication with the fluid passage, and a droplet generation tube having a first port and a second port, wherein the first port is in liquid communication with the accommodating cavity, an inner diameter of the second port is greater than 0.2 mm;

• wherein the droplet generation method comprises:
• S1, transferring a second liquid into the droplet generation tube, wherein the second liquid is a liquid immiscible with the first liquid;
• S2, inserting the droplet generation tube into the first liquid, and keeping the second port of the droplet generation tube being below the a liquid surface of the first liquid;
• and
• S3, while having the droplet generation tube and the droplet receiver remain stationary with respect to each other, controlling the volume of the accommodating cavity by subjecting the accommodating cavity to a periodic change while simultaneously injecting a driving fluid into the fluid passage to drive the second liquid to move, thereby generating droplets of the second liquid;
• wherein at least a part of a wall constituting the accommodating cavity is a movable part, a vibration mechanism is connected with the movable part, to subject the periodic change by making the movable part vibrate;
• wherein the periodic change is a compression-recovery reciprocating change, or an expansion-recovery reciprocating change, or a compression-recovery-expansion-recovery reciprocating change.