Drug delivery systems and methods for treating the nasal cavity

A delivery device for delivering a therapeutic agent to at least one of a palatine canal or a pterygopalatine fossa of a patient, the delivery device comprising:

• an elongated shaft with a proximal end and a distal end, wherein the elongated shaft comprises at least one lumen that extends through the elongated shaft to an output port at a distal portion of the elongated shaft, wherein the output port is proximal of the distal end of the elongated shaft;
• a handpiece coupled to the proximal end of the elongated shaft;
• and
• a boring element at the distal portion of the elongated shaft and configured to form a passage in a palatine bone;
• a therapeutic agent delivery member configured to deliver a therapeutic agent via the output port of the elongated shaft to the passage formed by the boring element;
• and
• one or more user control devices on the handpiece, wherein the one or more user control devices are operable to cause the boring element to form the passage in the palatine bone,
• wherein the boring element comprises:
• a needle that is configured to move through the output port and away from the elongated shaft to form the passage in the palatine bone responsive to an operation of the one or more user control devices, and
• a needle actuator that is configured to apply a force to the needle to cause the needle to (i) move through the output port and (ii) penetrate through the palatine bone responsive to operation of the one or more user control devices.