Back to results
US 12,678,572 B2Granted
Method for estimating inhale dose of a person
AssigneeMicrobase Technology Corp.
InventorsYu-Chung Hsu, Chien-Hua Lin, Hsin-Hua Tseng, Yi-Shou Chang, Jo-Ling Wu, Hui-Ling Lin
Life of this patent
Estimating the term…
Abstract
A method for estimating an inhale dose when a drug is delivered to a person using an inhaler is disclosed. A predicted inhale dose (PID) of the drug is estimated based on at least one first-type parameter and at least one second-type parameter. The first-type parameter is related to a breath pattern of the person, and the second-type parameter is related to the inhaler.
Claims15
A method for estimating an inhale dose when a drug is delivered to a person using an inhaler, the method comprising:
- obtaining, by an analyzer from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
- obtaining, by the analyzer, a second-type parameter related to the inhaler;
- estimating, by the analyzer, a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter;
- and
- showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
- PID=(TD−RC)*(I/(E+I))−DP+RP
- wherein TD is a total drug amount in an aerosol generator of the inhaler and obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and obtained from the aerosol generator, I is an inspiratory time of the person and derived from the breath pattern, E is an expiratory time of the person and derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and included in the second-type parameter.
4 more elements
An apparatus for estimating an inhale dose when a drug is delivered to a person using an inhaler, the apparatus comprising:
- a processor;
- and
- a memory storing instructions thereon, wherein the processor is capable of executing the instructions to perform the steps of:
- obtaining, from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
- obtaining a second-type parameter related to the inhaler;
- estimating a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter;
- and
- showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
- PID=(TD−RC)*(I/(E+I))−DP+RP
- wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second-type parameter.
7 more elements
A non-transitory storage medium with instructions stored thereon for estimating an inhale dose when a drug is delivered to a person using an inhaler, wherein a processor is capable of executing the instructions to perform the following steps:
- obtaining, by an analyzer from a breathing module, a first-type parameter related to a breath pattern of the person when the drug is delivered to the person through the inhaler;
- obtaining, by the analyzer, a second-type parameter related to the inhaler;
- estimating, by the analyzer, a predicted inhale dose of the drug after the drug is delivered to the person through the inhaler for a period of time, based on the first-type parameter and the second-type parameter;
- and
- showing the predicted inhale dose upon the predicted inhale dose being estimated by the analyzer, wherein the predicted inhale dose is estimated according to the following formula:
- PID=(TD−RC)*(I/(E+I))−DP+RP
- wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second-type parameter.
4 more elements
A method for delivering a drug to a person using an inhaler, comprising:
- inputting, to an analyzer, information related to a type of the inhaler;
- measuring, by a breathing module, a breath pattern of the person;
- and
- determining an inhale dose according to a predicted inhale dose of the drug shown by the analyzer after the drug is delivered to the person through the inhaler for a period of time, wherein the predicted inhale dose of the drug is estimated by the analyzer based on a first-type parameter related to the breath pattern of the person and a second-type parameter related to the inhaler, wherein the predicted inhale dose is estimated according to the following formula:
- PID=(TD−RC)*(I/(E+I))−DP+RP
- wherein TD is a total drug amount in an aerosol generator of the inhaler and is obtained from the aerosol generator, RC is a drug residue amount in the aerosol generator and is obtained from the aerosol generator, I is an inspiratory time of the person and is derived from the breath pattern, E is an expiratory time of the person and is derived from the breath pattern, DP is a drug deposit in an inlet path of the inhaler and is included in the second-type parameter, and RP is a drug reserve in an outlet path of the inhaler and is included in the second- type parameter.
3 more elements
Dependencies are inferred from the claim text.