Standardizations and medical devices for the preparation of platelet rich plasma (PRP) or bone marrow concentrate (BMC) alone or in combination with hyaluronic acid
AssigneeRegen Lab USA LLC
InventorAntoine Turzi
Life of this patent
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Abstract
The present invention is related to the field of tissue regeneration. It concerns more particularly new standardizations and medical devices for the preparation of A-PRP, PRP, BMC, fat tissue, alone or in combination with a biomaterial or cell extract.
Claims31
A container for preparation of any of plasma concentrate (PC) and bone marrow concentrate (BMC) in combination with at least one biomaterial,
- wherein the container is prefilled with the at least one biomaterial and at least one coagulation activator prior to introduction of blood or bone marrow for concentrate formation,
- wherein the container is sterile and under vacuum with the at least one biomaterial and at least one coagulation activator prefilled therein prior to use,
- wherein the at least one biomaterial is selected from hyaluronic acid, chitosan, silk protein or fibroin, cell extract, or any combination thereof, and
- wherein the at least one coagulation activator is selected from thrombin serum, calcium gluconate, calcium chloride, or any combination thereof.
A kit for preparation of any of plasma concentrate (PC) and bone marrow concentrate (BMC) in combination with at least one biomaterial selected from hyaluronic acid, chitosan, silk protein or fibroin, cell extract, or any combination thereof, wherein the kit comprises:
- a container, wherein the container is prefilled with the at least one biomaterial and at least one coagulation activator prior to introduction of blood or bone marrow for concentrate formation, wherein a prefilled combination of biomaterial and coagulation activator enhances stability of a resulting biomaterial-PC/BMC composition formed after introduction of the blood or bone marrow into the container, wherein the container is sterile and under vacuum with the at least one biomaterial and at least one coagulation activator prefilled therein prior to use, and wherein the at least one coagulation activator is selected from thrombin serum, calcium gluconate, calcium chloride, or a combination thereof;
- and
- a collection device to be affixed to the container for collecting any of blood and bone marrow into the container.
Dependencies are inferred from the claim text.