Algae-based microrobot for drug delivery
AssigneeThe Regents of the University of California
InventorsJoseph Wang, Liangfang Zhang, Fangyu Zhang, Jia Zhuang
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Abstract
Microalgae combined with antibiotic-loaded neutrophil membrane-coated polymeric nanoparticles provide a hybrid microrobot having robust locomotion in the lungs in vivo toward effective treatment of pulmonary and gastrointestinal tract infections. The algae-nanoparticle hybrid microrobots are provided in methods of treatment of disease or conditions by administration for active in vivo delivery of therapeutics to the lungs or gastrointestinal tract. The microrobot system can be applied to treat a wide range of diseases, including viral pneumonia.
Claims21
A hybrid microrobot comprising motile algae conjugated with a therapeutic agent-loaded cellular membrane-coated polymeric nanoparticle.
Dependencies are inferred from the claim text.