Aerosolized formulations of HIV protease inhibitors for the treatment of airway reflux
AssigneeThe Medical College of Wisconsin, Inc.
InventorNikki Johnston
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Abstract
The present invention provides methods of treating airway reflux using an HIV protease inhibitor that is capable of binding to and inhibiting the enzymatic activity of pepsin. Compositions comprising aerosolized formulations of HIV protease inhibitors are also provided.
Claims11
A method of treating reflux in a subject in need thereof, the method comprising administering a therapeutically effective amount of an HIV protease inhibitor to a subject to treat the reflux, wherein the HIV protease inhibitor is fosamprenavir and wherein the subject has an airway reflux condition selected from laryngopharyngeal reflux (LPR), gastropharyngeal reflux (GPR), and esophagopharyngeal reflux (EPR).
Dependencies are inferred from the claim text.