Back to results
US 12,678,399 B2Granted
Methods of improving autonomic imbalance or sympathetic impairment by regulating the stellate ganglion
AssigneeWest Virginia University Board of Governors on behalf of West Virginia University
InventorsAli R. Rezai, Milind Deogaonkar, Clay B. Marsh, Victor Finomore
Life of this patent
Estimating the term…
Abstract
Methods of improving ARDS by regulating a stellate ganglion is provided herein. Methods of improving a hypercoagulation state are also provided by regulating the sympathetic nervous system.
Claims19
A method of improving acute respiratory distress syndrome (ARDS) in a human patient suffering therefrom comprising:
- delivering a therapeutically effective dose of an anesthetic to the human patient's stellate ganglion (SG) to regulate function of the SG to improve the human patient's ARDS wherein the anesthetic is selected from lidocaine, bupivacaine or combinations thereof.
A method of improving ARDS in a patient suffering therefrom comprising the steps of:
- obtaining a measurement of a physiological parameter of the patient indicative of ANS imbalance and/or sympathetic impairment;
- and
- delivering a therapeutically effective dose of an anesthetic to the patient's stellate ganglion (SG) to regulate and optimize the function of the SG based on the measurement of the physiological parameter of the patient to improve the patient's ARDS wherein the anesthetic is selected from lidocaine, bupivacaine or combinations thereof.
A method of improving ARDS in a patient suffering therefrom comprising:
- obtaining a measurement of a baseline value of a physiological parameter of the patient indicative of ANS imbalance, sympathetic sensitization, sympathetic dysregulation and/or sympathetic impairment;
- delivering a therapeutically effective dose of an anesthetic to the patient's stellate ganglion (SG) to regulate function of the SG;
- obtaining a subsequent measurement of a resultant value of the physiological parameter of the patient during or after delivering the therapeutically effective dose of the anesthetic to the SG;
- obtaining a comparison of the resultant value to the baseline value to determine if the patient's ARDS has improved;
- and
- applying or adjusting delivery of the therapeutically effective dose of the anesthetic to the SG based upon a determination that the patient's ARDS has not improved to improve the patient's ARDS wherein the anesthetic is selected from lidocaine, bupivacaine or combinations thereof.
3 more elements
Dependencies are inferred from the claim text.