Multifunctional biopatch for wireless monitoring of health conditions and methods thereof

A condition-monitoring device comprising:

• an elastomer layer comprising a first side configured for conformal contact with a layer of skin and a second side, wherein the elastomer layer has a work of adhesion value from about 0.25 N/m to about 0.90 N/m;
• a first electrode positioned proximate the first side of the elastomer layer, the first electrode comprising one or more electrode units wherein the one or more electrode units comprises at least one of a positive electrode, negative electrode, or ground electrode, and wherein one or more electrode-unit circuits electrically interconnect the one or more electrode units allowing the one or more electrode units to stretch with the elastomer layer;
• a stretchable circuit board positioned proximate the second side of the elastomer layer and in electrical communication with the first electrode;
• a fluid layer constrained within the elastomer layer and disposed between the first electrode and the stretchable circuit board, the fluid layer for decoupling configured to decouple the first electrode from the stretchable circuit board and allowing the first electrode to move more freely with respect to the stretchable circuit board;
• a microcontroller in electrical communication with the stretchable circuit board and the first electrode;
• and
• a microelectromechanical system (MEMS) device in electrical communication with the microcontroller;
• wherein the first side of the elastomer layer is configured for the conformal contact, to adhere to the layer of skin without an adhesive when an adhesion energy of the elastomer layer is greater than a sum of an elastic energy of the skin and a bending energy of the first electrode;
• and
• wherein:
• the MEMS device is disposed on the stretchable circuit board;
• and
• the stretchable circuit board, the microcontroller, and the MEMS device are encapsulated within the elastomer layer.

A condition-monitoring device comprising:

• an elastomer layer having a first side configured for adhesive-free, conformal contact with a layer of skin and a second side, wherein the elastomer layer has a work of adhesion value from about 0.25 N/m to about 0.90 N/m;
• a positive electrode assembly comprising a first set of electrode units, wherein at least one of the electrode units of the first set is a positive electrode positioned proximate the first side of the elastomer layer, wherein one or more electrode-unit circuits electrically interconnect the first set of electrode units allowing the first set of electrode units to stretch with the elastomer layer;
• a first set of stretchable circuits in electrical communication with the first set of electrode units;
• a negative electrode assembly comprising a second set of electrode units, wherein at least one of the electrode units of the second set is a negative electrode positioned proximate the first side of the elastomer layer, wherein one or more electrode-unit circuits electrically interconnect the second set of electrode units allowing the second set of electrode units to stretch with the elastomer layer;
• a second set of stretchable circuits in electrical communication with the second set of electrode units;
• a stretchable circuit board disposed at least partially within the elastomer layer and is positioned proximate the second side of the elastomer layer, and the stretchable circuit board is in electrical communication with the positive and negative electrodes;
• a fluid layer constrained within the elastomer layer and disposed between (i) the positive electrode assembly and the negative electrode assembly and (ii) the stretchable circuit board and configured for decoupling (a) the positive electrode assembly and the negative electrode assembly from (b) the stretchable circuit board;
• a microcontroller electrically connected to the stretchable circuit board and in electrical communication with the positive and negative electrodes;
• a third stretchable circuit configured to provide electrical communication between the positive electrode and the stretchable circuit board;
• and
• a fourth stretchable circuit configured to provide electrical communication between the negative electrode and the stretchable circuit board;
• wherein the first set of stretchable circuits, the second set of stretchable circuits, the third stretchable circuit, and the fourth stretchable circuit are configured to stretch with the elastomer layer.