Systems and methods for color imaging
AssigneeBruker Nano, Inc.
InventorsMark Trulson, Koen Visscher, Kevin Newman
Life of this patent
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Abstract
Systems and methods for multi-color imaging using a microscope system. The microscope system can have a relatively small size as compared to an average microscope system. The microscope system can include various components configured to reduce or eliminate image artifacts such as chromatic aberrations and/or noise from stray light that can occur during multi-color imaging. The components can be configured to reduce or eliminate the image artifacts, and/or noise without substantially changing the size of the microscope system.
Claims24
A multi-color microscope apparatus comprising:
- an optical illumination system configured to direct therethrough a first light having a first spectrum and a second light having a second spectrum that is different from the first spectrum;
- an optical imaging system having a first lens configured to deliver a third light, emitted at a predetermined location outside of the multi-color microscope apparatus in response to irradiation of the predetermined location with the first light and/or the second light, towards a first optical element of the optical illumination system;
- an optical detection system optically separated from the first lens by the optical element and configured to form an image of the predetermined location in the third light delivered thereto by the optical imaging system, and
- an optical spectral filter separated from the predetermined location by the first lens, wherein spectral passbands or dead bands of the optical spectral filter are configured to minimize or prevent stray light from reaching the optical detection system.
A method for multi-color microscopic imaging, the method comprising:
- directing a first light through an optical illumination system of a multi-color microscope apparatus and/or directing a second light through the optical illumination system onto a first lens of an optical imaging system of the multi-color microscope apparatus;
- delivering said first light and/or said second light through the first lens to a predetermined location;
- transmitting, through the first lens, light emission that has been formed at the predetermined location, and
- receiving, at a detector of the multi-color microscope apparatus, said light emission that has been transmitted through the first lens, through a corrective element configured to correct chromatic aberration, and through an optical spectral filter disposed between the first lens and the detector,
- wherein spectral passbands or dead bands of the optical spectral filter are configured to minimize or prevent stray light from reaching the detector.
Dependencies are inferred from the claim text.