Unit for filtering leukocytes with reduced platelet adhesion
AssigneeMaco Pharma
InventorLaurent Ducoroy
Life of this patent
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Abstract
The invention relates to a filtration unit for enabling the selective leucocytapheresis of a fluid containing blood platelets. The filtration unit includes an external pouch provided with an inlet orifice and an outlet orifice, the pouch enclosing a porous element interposed between the orifices. The porous element encloses a leucocytapheresis medium impregnated with a polymer, the polymer having the general formula -(A)m-(B)n- (I), wherein A is a unit originating from an alkoxyalkyl acrylate or alkoxyalkyl methacrylate monomer, B is a unit originating from a hydrophobic polymerisable monomer, and m and n are integers, the sum of which, m+n, is equal to 100, m being an integer greater than 80.
Claims17
A filtration unit for allowing the selective leukodepletion of a fluid containing blood platelets comprising an outer housing provided with at least one inlet port and at least one outlet port, the outer housing enclosing a porous element interposed between the ports, the porous element enclosing a leukodepletion medium impregnated with a polymer, the polymer having the general formula-(A)m-(B)n-(I), in which A is an alkoxyalkyl acrylate or an alkoxyalkyl methacrylate monomer, B is a hydrophobic polymerizable monomer, and m and n are integers of which the sum m+n is equal to 100, m being an integer greater than 80.
A filtration unit for allowing the selective leukodepletion of a fluid containing blood platelets comprising an outer housing provided with at least one inlet port and at least one outlet port, the outer housing enclosing a porous element interposed between the ports, the porous element enclosing a leukodepletion medium impregnated with a polymer, the polymer having the general formula-(A)m-(B)n-(I), in which A is an alkoxyalkyl acrylate or an alkoxyalkyl methacrylate monomer, B is a hydrophobic polymerizable monomer, and m and n are integers of which the sum mtn is equal to 100, m being an integer greater than 80;
- and wherein B is a monomer chosen from the group consisting of an alkyl acrylate, an alkyl methacrylate and a vinyl alkylate.
A filtration unit for allowing the selective leukodepletion of a fluid containing blood platelets comprising an outer housing provided with at least one inlet port and at least one outlet port, the outer housing enclosing a porous element interposed between the ports, the porous element enclosing a leukodepletion medium impregnated with a polymer, the polymer having the general formula-(A)m-(B)n-(I), in which A is an alkoxyalkyl acrylate or an alkoxyalkyl methacrylate monomer, B is a hydrophobic polymerizable monomer, and m and n are integers of which the sum m+n is equal to 100, m being an integer greater than 80;
- and wherein B does not contain a basic nitrogen group.
Dependencies are inferred from the claim text.