System for shape memory alloy enabled drug release

A drug delivery system carrying an active substance for treating various diseases in a body, wherein said drug delivery system comprises:

• a shape memory alloy wire forming a main structure of the drug delivery system, wherein the shape memory alloy wire provides a specific movement to a target tissue or a target organ, wherein a drug is configured to be released to the target tissue or the target organ, and the shape memory alloy wire provides release of an active substance in a controlled manner and orients at a certain angle after reaching a vicinity of the target tissue or the target organ;
• a hydrogel coating to encapsulate said shape memory alloy wire, wherein the hydrogel acts as a coating to said shape memory alloy wire to prevent release of toxic ions to the body and a drug loaded hydrogel carries the drug within the body;
• and the active substance to be delivered to the target organ or the target tissue;
• wherein the drug delivery system is configured to be directed to the target organ or the target tissue and bends at an angle between 5° and 175° once the drug delivery system reaches the target organ or the target tissue to release the active substance by an actuation of the shape memory alloy wire via bending the hydrogel coating;
• wherein said hydrogel coating is obtained from a mixture of gelatin and PVA materials;
• and wherein the drug delivery system further comprises a catheter, the shape memory alloy wire being attached to a distal end portion of the catheter such that the hydrogel-coated wire is deliverable to and removable from the body by means of the catheter.