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US 12,673,137 B2Granted
Therapeutic putties containing additives including processed human blood plasma
AssigneeAbyrx, Inc.
InventorsRichard L. Kronenthal, John Pacifico, Aniq Darr
Life of this patent
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Abstract
Provided herein are settable and non-settable compositions for use in surgical procedures comprising a variety of disclosed particles and optionally including previously unclotted, lyophilized, optionally crosslinked mammalian blood plasma. Also provided are related compositions, including surgical kits and packages, as well as methods of making and using the compositions.
Claims30
A plurality of biocompatible, settable component parts, comprising a first component and a second component,
- wherein the first component comprises about 30% to 50% of an isocyanate component and about 40% to 80% of a first particulate component, based upon the total weight of the first component,
- wherein the second component comprises a component comprising active hydrogen functional groups and 40% to 80% of a second particulate component, based upon the total weight of the second component,
- wherein the first and the second components are mixed together prior to use to form a bioabsorbable, homogenous, hemostatic and adhesive composition.
Dependencies are inferred from the claim text.