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US 12,673,128 B2Granted
Nano fibrous polyelectrolyte complex for rapid control of hemorrhage
AssigneeNational Institute of Technology Rourkela
InventorsDevendra Verma, Sabir Hossain
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Abstract
A polyelectrolyte complex includes nanofibers. The nanofibers include at least one polycationic component and at least one polyanionic component. The nanofibers have a diameter in a range of 20-100 nm. A process for preparing the complex, a method of using the complex, a kit which includes the complex, and a method of inhibiting loss of blood from a wound site by applying the complex to the wound site are also provided.
Claims8
A process for preparing a polyelectrolyte complex comprising nanofibers, said process comprising:
- (a) obtaining a solution-I comprising at least one polycationic component having a pH in a range of 3-5 (b) obtaining a solution-II comprising at least one polyanionic component having a pH in a range of 6-8;
- (c) mixing the solution-I and the solution-II by adding solution-I dropwise to solution-II to obtain a mixture;
- and (d) processing the mixture, wherein the processing comprises (i) sonicating the mixture to obtain a sonicated sample;
- and (ii) washing the sonicated sample with at least one organic solvent followed by drying the sample, in order to obtain the polyelectrolyte complex, wherein the complex has a pH in a range of 3-7.
1 more element
Dependencies are inferred from the claim text.