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US 12,673,084 B2Granted
Compositions and methods for combinatorial drug discovery in nanoliter droplets
AssigneesThe Broad Institute, Inc., Massachusetts Institute of Technology
InventorsPaul Blainey, Anthony Kulesa, Jared Kehe
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Abstract
Compounds and methods for combinatorial drug discovery in nanoliter droplets are described herein. More particularly, novel synergistic agents that increase efficacy of antibiotic agents to treat bacterial infections are described.
Claims6
A composition comprising (i) a somatostatin receptor agonist and (ii) novobiocin.
A method of treating a subject having a bacterial infection, the method comprising administering to the subject (i) an effective amount of an antibiotic selected from the group consisting of novobiocin, erythromycin, and combination thereof;
- and (ii) an effective amount of Lanreotide.
Dependencies are inferred from the claim text.