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US 12,673,062 B2Granted
Combination therapy of tetracyclic quinolone analogs for treating cancer
AssigneeSenhwa Biosciences, Inc.
InventorJohn Soong
Life of this patent
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Abstract
The present invention provides methods, compositions, and combinations for treating cancer via combined use of a compound of formula I or a pharmaceutically acceptable salt, ester, solvate and/or prodrug thereof, wherein A, Q, n, m, R7, R8, V, X1, X2, X3, X4, X5, X6, and X7 are as defined herein, and at least one therapeutically active agents selected from immunotherapeutics, anticancer agents, and anti-angiogenics.
Claims9
A pharmaceutical combination comprising a therapeutically effective amount of Compound A:
- or a pharmaceutically acceptable salt, ester, solvate and/or prodrug thereof;
- and at least one PARP inhibitor, wherein the PARP inhibitor is Olaparib or talazoparib.
Dependencies are inferred from the claim text.