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US 12,672,813 B2Granted
Arrhythmia classification using measurement of cardiac activity and power analysis
AssigneeThe Regents of the University of Michigan
InventorsGrant Kruger, Hakan Oral, Omer Berenfeld
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Abstract
The following relates generally to an injectable cardiac monitor. In some embodiments, an injectable cardiac monitor includes: a sensor configured to detect a cardiac signal from a mammal, a processor configured to process the detected cardiac signal, a transmitter configured to transmit the processed signal to a computing device, and a capsule for injecting into the mammal. In some implementations, the capsule includes: a body configured to enclose all of the sensor, the processor, and the transmitter, and wings configured to, upon deployment into the mammal, deploy outwardly from the body of the capsule.
Claims19
An injectable cardiac monitor device, comprising:
- a sensor configured to detect a cardiac signal from a mammal;
- a transmitter configured to transmit the cardiac signal to a computing device;
- and
- a capsule for injecting into the mammal, the capsule comprising:
- a body configured to enclose all of the sensor and the transmitter;
- a wing configured to, upon deployment into the mammal, deploy outwardly from the body of the capsule;
- and
- a coil configured to power a capacitor stage within the device by inductively harvesting energy from an external charging device, wherein the capacitor stage is configured to provide power to the sensor and to the transmitter, and wherein the coil is included in the wing.
5 more elements
An injectable cardiac monitor device, comprising:
- a sensor configured to detect a cardiac signal from a mammal;
- a transmitter configured to transmit the cardiac signal to a computing device;
- and
- a capsule for injecting into the mammal, the capsule comprising:
- a body configured to enclose all of the sensor and the transmitter;
- a wing configured to, upon deployment into the mammal, deploy outwardly from the body of the capsule;
- and
- a processor configured to process the detected cardiac signal, and wherein the body of the capsule is further configured to enclose the processor;
- wherein:
- the sensor is an Electrocardiogram (ECG) sensor;
- and
- the processor is configured to:
- determine if arrhythmia is suspected;
- if arrhythmia is suspected, increase power intake to the processor, and perform additional analysis on the cardiac signal;
- if the additional analysis indicates an arrhythmia, record the processed signal to random access memory (RAM);
- and
- once the RAM reaches a predetermined storage capacity, at least one of:
- (i) save the processed signal in RAM to a flash memory, (ii) wirelessly transmit the processed signal to the computing device, or (iii) pause the recording of the processed signal to RAM in order to wait to be interrogated by the computing device.
15 more elements
An injectable cardiac monitor device, comprising:
- a sensor configured to detect a cardiac signal from a mammal;
- a transmitter configured to transmit the cardiac signal to a computing device;
- and
- a capsule for injecting into the mammal, the capsule comprising:
- a body configured to enclose all of the sensor and the transmitter;
- and
- a wing configured to, upon deployment into the mammal, deploy outwardly from the body of the capsule;
- wherein:
- the sensor is an electrocardiogram sensor, and the detected cardiac signal is an electrocardiogram signal;
- and
- the device further comprises a processor comprising:
- an input stage to receive the electrocardiogram signal, wherein the input stage is a real-time dynamically adjustable signal transformation stage configured to condition the electrocardiogram signal;
- an analysis stage coupled to the input stage to receive the conditioned electrocardiogram signal from the input stage, wherein the analysis stage comprises,
- a transformation stage wherein a frequency, time, or phase domain representation of the conditioned electrocardiogram signal is formed from the conditioned electrocardiogram signal being in a time-domain signal, and
- an evaluation stage, wherein frequency, time or phase domain features related to arrhythmias are extracted from the frequency, time, or phase domain representation, wherein the evaluation stage is configured to determine a summed energy over a predetermined range of frequencies, time intervals or phases for the frequency, time, or phase domain representation and configured to normalize the summed energy to the energy at the frequency within the predetermined range of frequencies having the maximum energy to form a spectral frequency dispersion metric (SFDM), spectral time domain dispersion metric (STDM), and/or spectral phase domain dispersion metric (SPDM) over the predetermined range of frequencies, time intervals, or phases;
- and
- a classification stage coupled to the evaluation stage to receive the SFDM, STDM, and/or SPDM and to determine whether the mammal is experiencing the arrhythmias.
14 more elements
An injectable cardiac monitor device, comprising:
- a sensor configured to detect a cardiac signal from a mammal;
- a transmitter configured to transmit the cardiac signal to a computing device;
- and
- a capsule for injecting into the mammal, the capsule comprising:
- a body configured to enclose all of the sensor and the transmitter;
- and
- a wing configured to, upon deployment into the mammal, deploy outwardly from the body of the capsule;
- wherein:
- the sensor is an electrocardiogram sensor;
- and
- the computing device comprises:
- an input stage to receive an electrocardiogram signal as the signal transmitted to the computing device, wherein the input stage is a real-time dynamically adjustable signal transformation stage configured to condition the electrocardiogram signal;
- an analysis stage coupled to the input stage to receive the conditioned electrocardiogram signal from the input stage, wherein the analysis stage comprises,
- a transformation stage wherein a frequency, time, or phase domain representation of the conditioned electrocardiogram signal is formed from the conditioned electrocardiogram signal being in a time-domain signal, and
- an evaluation stage, wherein frequency, time or phase domain features related to arrhythmias are extracted from the frequency, time, or phase domain representation, wherein the evaluation stage is configured to determine a summed energy over a predetermined range of frequencies, time intervals or phases for the frequency, time, or phase domain representation and configured to normalize the summed energy to the energy at the frequency within the predetermined range of frequencies having the maximum energy to form a spectral frequency dispersion metric (SFDM), spectral time domain dispersion metric (STDM), and/or spectral phase domain dispersion metric (SPDM) over the predetermined range of frequencies, time intervals, or phases;
- and
- a classification stage coupled to the evaluation stage to receive the SFDM, STDM, and/or SPDM and to determine whether the mammal is experiencing the arrhythmias.
14 more elements
Dependencies are inferred from the claim text.