Delivery systems and devices for the treatment of benign prostatic hyperplasia and related lower urinary tract symptoms

A device for delivering and deploying an implant at a desired location in a lumen of a body, comprising:

• an elongated sheath having an atraumatic tip at a distal end of the elongated sheath, the atraumatic tip having a lumen connecting an open proximal end and an open distal end, the elongated sheath being configured for introduction through a working channel of a cystoscope having a lumen for maintaining the implant in a constrained configuration within the elongated sheath adjacent to the atraumatic tip;
• a handle secured to a proximal end of the elongated sheath;
• a pusher coaxially disposed within the elongated sheath;
• a deployment actuator associated with the handle and coupled to the pusher, wherein manipulation of the deployment actuator results in relative motion between the pusher and the elongated sheath to cause the implant maintained in the constrained configuration within the elongated sheath adjacent the atraumatic tip to be pushed out of the open distal end of the atraumatic tip of the elongated sheath at the desired location in the body lumen;
• and
• a rotation locking knob on the handle configured to selectively engage a luer connector hub of the cystoscope to prevent rotation of the delivery device relative to the cystoscope during deployment of the implant.

A method for delivering and deploying an implant at a desired location in a lumen of body, comprising:

• providing:
• i) an elongated sheath having an atraumatic distal tip at a distal end of the elongated sheath, the atraumatic tip having a lumen connecting an open proximal end and an open distal end, the elongated sheath being configured for introduction through a working channel of a cystoscope and having a lumen for maintaining the implant in a constrained configuration within the elongated sheath adjacent the atraumatic tip, ii) a handle secured to a proximal end of the elongated sheath, iii) a pusher disposed within the elongated sheath and configured to push the implant out of the open distal end of the atraumatic tip at the target site within the body lumen, iv) a deployment actuator associated with the handle and coupled to the pusher, wherein manipulation of the deployment actuator results in relative motion between the pusher and the elongated sheath to cause the implant to be deployed from the open distal end of the atraumatic tip of the elongated sheath, and v) a rotation locking knob on the handle configured to selectively engage a luer connector hub of the cystoscope to prevent rotation of the delivery system relative to the cystoscope during deployment of the implant;
• introducing the elongated sheath through the working channel of the cystoscope;
• positioning the distal tip at target site within the body lumen;
• and
• manipulating the deployment actuator to result in relative motion between the pusher and the elongated sheath to cause the implant to be pushed out of the open distal end of the atraumatic tip of the elongated sheath.