tTG-DGP biomarkers for monitoring celiac disease
AssigneesVibrant Holdings, LLC, Mayo Foundation for Medical Education and Research
InventorsRok Seon Choung, Eric V. Marietta, Vasanth Jayaraman, Karthik Krishna, Joseph A. Murray
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Abstract
The present disclosure relates generally to biomarkers and peptide arrays, and, more particularly, to a method of using a peptide array to identify biomarkers for an autoimmune disease such as, e.g., Celiac disease. Furthermore, a set of novel biomarkers for Celiac disease, having high sensitivity and specificity, are disclosed in addition to method of treatment using the novel biomarkers.
Claims6
An array comprising an array surface and at least two linear peptide probes, wherein each of the at least two linear peptide probes comprises a binding motif selected from the group consisting of SEQ ID NOS:
- 1-172, and wherein the at least two peptide probes extend from the array surface.
A peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOS:
- 1-172.
Dependencies are inferred from the claim text.