Lock mass correction during chromatography void time

A scientific instrument support system, comprising:

• sample analysis logic to cause a sample to be injected into a gas chromatograph and to obtain a mass spectrum of the sample using a mass spectrometer coupled to the output of the gas chromatograph, the mass spectrometer utilizing a mass calibration or a lock mass correction while obtaining the mass spectrum of the sample;
• calibration gas logic to control a supply of a calibration gas to the mass spectrometer during the void time of the gas chromatograph;
• and
• lock mass calibration logic to obtain a mass spectrum of the calibration gas using the mass spectrometer during the void time of the gas chromatograph, to calculate the mass calibration or the lock mass correction to be used by the sample analysis logic, to turn on a filament of an ion source, a high voltage DC device, a high voltage RF device, or any combination thereof during the void time to obtain the mass spectrum of the calibration gas, and to turn off the filament, the high voltage DC device, the high voltage RF device, or the combination thereof prior to a solvent peak.