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US 12,668,600 B2Granted
Substituted heteroaromatic amines and uses thereof
AssigneeKumquat Biosciences Inc.
InventorsBaogen Wu, Pingda Ren, Liansheng Li
Life of this patent
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Abstract
The present disclosure provides compounds and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic protein.
Claims16
A compound of Formula:
- or a pharmaceutically acceptable salt or solvate thereof, wherein:
- R2 is selected from
- R3 is independently selected at each occurrence from C1-6 alkyl, C2-6 alkenyl, and C2-6 alkynyl, each of which is optionally substituted with one, two, or three substituents independently selected from halogen and —CN;
- R6 is selected from hydrogen, halogen, and C1-3 haloalkyl;
- m is 0, 1, 2, or 3;
- and
- n is 1 or 2.
4 more elements
A compound having the formula
- or a salt or solvate thereof.
A compound having the formula
- or a salt or solvate thereof.
Dependencies are inferred from the claim text.