Back to results
US 12,668,567 B2Granted
Modified forms of ambroxol for therapeutic use
AssigneeZywie Inc.
InventorsStephen Anderson, Stephen Pasternak, Vincent Jacques, Gerard Joseph Broussard, Jr.
Life of this patent
Estimating the term…
Abstract
The invention relates to analog forms of ambroxol and related compounds, compositions comprising same, and methods of preventing and/or treating various diseases and medical conditions involving the administration of analogs of ambroxol and related compounds.
Claims26
A compound according to Formula I:
- wherein
- indicates that the associated R or X group can be attached to any available carbon atom on the phenyl ring,
- Ra is hydroxyl (OH),
- Rb is H,
- Rc and Rd are each independently selected from H or a C1-3 alkyl or Rc and Rd are each part of a 4, 5, 6 or 7 membered ring structure that connects Rc and Rd,
- each of R1 to R14 is independently selected from H and D,
- X1 and X2 are independently selected from F, Cl, Br, and I, with the proviso that X1 and X2 are not both Br;
- or a pharmaceutically acceptable salt, solvate or prodrug thereof.
5 more elements
Dependencies are inferred from the claim text.