Use of cysteamine and derivatives thereof to suppress tumor metastases
AssigneesMeshaberase, LLC, The United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsBenjamin Rubin, Mark Gilbert, Jinkyu Jung
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Abstract
The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
Claims13
A method of prolonging survival in a human subject with malignant glioma comprising administering to the human subject with malignant glioma, cysteamine, cystamine, or pharmaceutically acceptable salt thereof, in an effective amount to inhibit or suppress tumor cell invasion or to inhibit or suppress metastasis of the malignant glioma, to prolong survival of the human subject with malignant glioma, wherein the effective amount is less than an amount cytotoxic to the malignant glioma.
Dependencies are inferred from the claim text.