Assembly and method for the closure of vascular abnormalities

A method of securing a patch to tissue at a target site, the method comprising:

• positioning a patch delivery assembly at the target site, the patch delivery assembly including (i) a patch installation frame including a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough, (ii) a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen, and (iii) a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism, wherein, in a deployment configuration of the patch delivery assembly, the patch delivery assembly further includes a patch releasably coupled to the distal end of the patch installation frame, wherein the patch installation frame comprises a folded braided shape-memory material and has a tapered wall defining a cavity therein;
• deploying the patch installation frame from a delivery catheter, said deploying comprising (a) expanding the patch installation frame from a constricted delivery configuration to an expanded deployment configuration and (b) simultaneously expanding the patch coupled to the patch installation frame;
• abutting the distal end of the patch installation frame and the patch against tissue at the target site;
• securing the patch to the tissue using the securement mechanism;
• and
• de-coupling the patch from the patch installation frame.