US 12,667,296 B2Granted

Adjustment of long term intraindividual changes in precordial ECG amplitudes

AssigneeBIOPOTENTIAL Oy Ltd

InventorsHeikki Riekkinen, Tommi Riekkinen, Annika Kolari

Life of this patent

Estimating the term…

Loading patent…

Abstract

The present disclosure lies in the general field of clinical electrocardiography (ECG), more specifically in ECG methods comprising precordial ECG amplitude measurements. The present invention relates to methods of determining a subject's corrected precordial ECG amplitude from an ECG measurement, which corrections are based on intraindividual changes such as the rotation position of the heart on the horizontal plane, and/or changes in body mass index. The methods are thus useful for adjustment of intraindividual changes over time in precordial ECG amplitudes, such as between two ECG measurements. The present invention further relates to a device, an apparatus and a computer program product, and to uses of said device, apparatus and computer program product in a method of determining a subject's corrected precordial ECG amplitude from an ECG measurement, and for improving the accuracy of electrocardiographic methods depending on precordial ECG amplitude measurements. For example, the methods and the device, apparatus or product can be advantageously used in a method of diagnosing left ventricular hypertrophy and/or hypertension in a subject.

Claims4

Dependent claims

An apparatus (601) for determining a subject's corrected precordial ECG amplitude in an ECG measurement, comprising:

at least one processor (620), and
at least one memory (630) for storing instructions (631) to be executed by the at least one processor (620), wherein the at least one memory (630) and the instructions are configured to, with the at least one processor (620), cause the apparatus (601) at least to perform:
maintaining (301), in said at least one memory, said subject's ECG data obtained from a first ECG measurement made at a first time point, wherein said ECG was recorded using a standardized and reproducible electrode placement method, and wherein said ECG data comprises data for a six lead V1-V6 precordial ECG;
maintaining (302), in said at least one memory, said subject's ECG data obtained from a second ECG measurement made at a second time point, which is after the first time point, wherein said ECG was recorded using a standardized and reproducible electrode placement method, and wherein said ECG data comprises data for a six lead V1-V6 precordial ECG and a precordial ECG amplitude A;
determining (303) a percentage correction value R by determining the position of the transition zone in said data of a six lead V1-V6 precordial ECG from said first ECG measurement and assigning (303) to it a percentage correlation value R1, and determining (303) the position of the transition zone in said data of a six lead V1-V6 precordial ECG from said second ECG measurement and assigning (303) to it a percentage correlation value R2, wherein R1 or R2 is independently
(i) about −30% in case the transition zone is between lead V1 and lead V2,
(ii) about −20% in case the transition zone is around lead V2,
(iii) about −10% in case the transition zone is between lead V2 and lead V3,
(iv) about 0 in case the transition zone is around lead V3 or between lead V3 and lead V4,
(v) about 10% in case the transition zone is around lead V4,
(vi) about 20% in case the transition zone is between lead V4 and lead V5,
(vii) about 30% in case the transition zone is around lead V5, and
(viii) about 40% in case the transition zone is between lead V5 and lead V6;
and calculating (303) the percentage correction value R using formula (1)
R
=
R
⁢
2
-
R
⁢
1
;
and
(
1
)
calculating (304) a subject's corrected precordial ECG amplitude A* from a precordial ECG amplitude value A from said ECG measurement from said second time point, and the percentage correction value R, using formula (2)
A
*
=
A
+
(
R
×
A
)
;
(
2
)
thereby determining said subject's corrected precordial ECG amplitude in the ECG measurement;
and
outputting (305) said subject's corrected precordial ECG amplitude.

43 more elements

A computer program product, embodied on a non-transitory computer readable medium, comprising program instructions, that when run is adapted to determine a subject's corrected precordial ECG amplitude in an ECG measurement by performing:

maintaining (301), in said at least one memory, said subject's ECG data obtained from a first ECG measurement made at a first time point, wherein said ECG data was recorded using a standardized and reproducible electrode placement method, and wherein said ECG data comprises data for a six lead V1-V6 precordial ECG;
maintaining (302), in said at least one memory, said subject's ECG data obtained from a second ECG measurement made at a second time point, which is after the first time point, wherein said ECG was recorded using a standardized and reproducible electrode placement method, and wherein said ECG data comprises data for a six lead V1-V6 precordial ECG and a pre-cordial ECG amplitude A;
determining (303) a percentage correction value R by determining the position of the transition zone in said data of a six lead V1-V6 precordial ECG from said first ECG measurement and assigning (303) to it a percentage correlation value R1, and determining (303) the position of the transition zone in said data of a six lead V1-V6 precordial ECG from said second ECG measurement and assigning (303) to it a percentage correlation value R2, wherein R1 or R2 is independently
(i) about −30% in case the transition zone is between lead V1 and lead V2,
(ii) about −20% in case the transition zone is around lead V2,
(iii) about −10% in case the transition zone is between lead V2 and lead V3,
(iv) about 0 in case the transition zone is around lead V3 or between lead V3 and lead V4,
(v) about 10% in case the transition zone is around lead V4,
(vi) about 20% in case the transition zone is between lead V4 and lead V5,
(vii) about 30% in case the transition zone is around lead V5, and
(viii) about 40% in case the transition zone is between lead V5 and lead V6;
and calculating (303) the percentage correction value R using formula (1)
R
=
R
⁢
2
-
R
⁢
1
;
and
(
1
)
calculating (304) a subject's corrected precordial ECG amplitude A* from a precordial ECG amplitude value A from said ECG measurement from said second time point, and the percentage correction value R, using formula (2)
A
*
=
A
+
(
R
×
A
)
;
(
2
)
thereby determining said subject's corrected precordial ECG amplitude in the ECG measurement;
and
causing (305) outputting said subject's corrected precordial ECG amplitude.

41 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/265,253Filed 2 Dec 2021
Published: US 2024/0041380 A18 Feb 2024
Granted: 30 Jun 2026
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

A61B 5/346
Heart-related electrical modalities, e.g. electrocardiography [ECG]: analysis of electrocardiograms
A61B 5/352
Detecting specific parameters of the electrocardiograph cycle: detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
A61B 5/303
Input circuits therefor: patient cord assembly, e.g. cable harness
A61B 5/338
Recording apparatus specially adapted therefor: recording by printing on paper