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US 12,667,129 B1Granted
Nicotine pouches for smoking cessation
AssigneeNAQA Holding Ltd
InventorsJames Preston Campbell, Sameena Kathryn Masood-Campbell, Keaton James Campbell
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Abstract
Provided herein, according to an embodiment, is a nicotine-containing moist granulate composition comprising: nicotine or a pharmaceutically acceptable salt thereof; mannitol, and cellulose; the composition having a total moisture content of between 35-45%. The granulate shows favorable organoleptic qualities such as taste and mouthfeel and is free flowing to enable packaging in pouches. Optionally, the composition further comprises an oral health enhancing agent.
Claims19
A nicotine-containing moist granulate composition comprising:
- nicotine, or a pharmaceutically acceptable salt thereof, in an amount of nicotine free base equivalent between 0.1-4% by weight of the non-aqueous portion of the composition;
- mannitol in an amount of between 38-45% by weight of the non-aqueous portion of the composition;
- microcrystalline cellulose in an amount of between 28-38% by weight of the non-aqueous portion of the composition;
- and total moisture of between 35-45%, wherein the composition has a mean particle diameter of between 50 and 250 micrometer.
1 more element
Dependencies are inferred from the claim text.