Methods and user interfaces for designing cell-based screening assay experiments

A system for designing a cell-based screening assay experiment, the system comprising:

• at least one processor and memory addressable by the at least one processor, the memory storing at least one program for execution by the at least one processor, the at least one program comprising instructions for:
• displaying a graphical user interface;
• at the graphical user interface:
• (1) receiving a first user input identifying a template plate definition for the cell-based screening assay experiment, the template plate definition including one or more pluralities of template test wells and at least one template control well;
• (2) receiving a second user input defining (A) one or more sets of disease reagents associated with a first plurality of template test wells in the one or more pluralities of template test wells, and (B) at least one destination concentration for the one or more sets of disease reagents;
• (3) receiving a third user input defining (A) a first set of treatment reagents, (B) at least one destination concentration for the first set of treatment reagents, (C) a number of replicates of the first set of treatment reagents, and (D) a selection to associate the first set of treatment reagents with a first set of disease reagents in the one or more sets of disease reagents;
• automatically generating, based at least partially on the first user input, the second user input and the third user input, a design for the cell-based screening assay experiment, the automatically generating including:
• (i) determining, from among the one or more pluralities of template test wells, a number of template test wells required for performing the cell-based screening assay experiment, thereby defining a first plurality of test wells in the design;
• and
• (ii) distributing the first plurality of test wells over one or more test plates in the design, wherein each test plate in the one or more test plates is an instance of the template plate definition.

A non-transitory computer readable media storing one or more programs, the one or more programs comprising instructions, which when executed by an electronic device with a display cause the electronic device to:

• display a graphical user interface;
• at the graphical user interface:
• (1) receive a first user input identifying a template plate definition for the cell-based screening assay experiment, the template plate definition including one or more pluralities of template test wells and at least one template control well;
• (2) receive a second user input defining (A) one or more sets of disease reagents associated with a first plurality of template test wells in the one or more pluralities of template test wells, and (B) at least one destination concentration for the one or more sets of disease reagents;
• (3) receive a third user input defining (A) a first set of treatment reagents, (B) at least one destination concentration for the first set of treatment reagents, (C) a number of replicates of the first set of treatment reagents, and (D) a selection to associate the first set of treatment reagents with a first set of disease reagents in the one or more sets of disease reagents;
• automatically generate, based at least partially on the first user input, the second user input and the third user input, a design for the cell-based screening assay experiment, the automatically generating including:
• (i) determining, from among the one or more pluralities of template test wells, a number of template test wells required for performing the cell-based screening assay experiment, thereby defining a first plurality of test wells in the design;
• and
• (ii) distributing the first plurality of test wells over one or more test plates in the design, wherein each test plate in the one or more test plates is an instance of the template plate definition.