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US 12,663,358 B2Granted
Apparatuses, systems and methods for imaging flow cytometry
AssigneeLife Technologies Corporation
InventorsGregory Kaduchak, Michael Ward
Life of this patent
Estimating the term…
Abstract
The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.
Claims20
A method, comprising:
- selectively sorting at least some of a population of particles into a sorted particle subpopulation,
- the selective sorting being performed on the basis of comparing a record associated with a given particle to predetermined gating conditions;
- and
- recording an image of at least a particle sorted into the sorted particle subpopulation.
1 more element
A method, comprising:
- selectively recording an image of at least one particle within an imaged particle subpopulation of particles,
- the selective recording being performed on the basis of comparing a record associated with the at least one particle to predetermined gating conditions;
- and sorting the at least one particle into a sorted particle subpopulation.
A system, comprising:
- a flow path configured to communicate particles therethrough;
- a first train,
- the first train configured to illuminate at least one particle at a location along the flow path and the first train being configured to derive for the at least one particle a record associated with illumination of the at least one particle by the first train;
- and
- a second train,
- the second train being configured to selectively sort particles into a sorted particle subpopulation on the basis of comparing the record of a particle to predetermined gating conditions and the second train being configured to record an image of a particle of the sorted particle subpopulation.
3 more elements
A system, comprising:
- a first flow path configured to communicate particles therethrough;
- a first train,
- the first train configured to illuminate at least one particle at a location along the flow path and the first train configured to derive for the at least one particle a record associated with illumination of the at least one particle by the first train;
- and
- a second train,
- the second train being configured to selectively sort particles into a sorted particle subpopulation of particles, the selective sorting being performed on the basis of comparing the record associated with a particle to predetermined gating conditions, and the second train being configured to move particles of the sorted particle subpopulation into any one or more of a second flow path, a chamber, or a region of a flow in the first flow path that has a speed different than a speed at the location along the flow path.
3 more elements
Dependencies are inferred from the claim text.