Back to results
US 12,662,526 B2Granted
Anti-dengue virus antibodies having cross-reactivity to zika virus and methods of use
AssigneesChugai Seiyaku Kabushiki Kaisha, Agency for Science, Technology and Research
InventorsKatja Fink, Cheng-I Wang, Lisa Fong Poh Ng, Laurent Renia, Zenjiro Sampei, Xing'er Christine Koo
Life of this patent
Estimating the term…
Abstract
The disclosure provides anti-DENV antibodies having a cross-reactivity to ZIKV and methods of making and using the same. The anti-DENV antibodies have uses that include treating or preventing ZIKV infection.
Claims5
A method for treating or preventing Dengue virus infection, comprising administering an antibody that binds to Zika virus, wherein the antibody comprises:
- (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO:
- 12, (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO:
- 15, (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO:
- 20, (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO:
- 21, (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO:
- 24 and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO:
- 27.
4 more elements
Dependencies are inferred from the claim text.