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US 12,662,515 B2Granted
Fusion protein comprising BP26 and antigenic polypeptide
AssigneeKorea Advanced Institute of Science and Technology
InventorsSangyong Jon, Sukmo Kang, Yujin Kim, Ji-Joon Song
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Abstract
The present disclosure relates to a fusion protein comprising BP26 and an antigenic polypeptide, and to a nanoarchitecture comprising same. A vaccine composition comprising the fusion protein, nanoarchitecture, or combination thereof of the present disclosure can be used to effectively prevent or treat pathogens or cancer, and thus can be used as a multi-purpose vaccine platform.
Claims12
A nanoarchitecture comprising a fusion protein comprising BP26 and an antigenic polypeptide,
- wherein the antigenic polypeptide is linked to the C-terminus of the BP26, and no antigenic polypeptide is linked to the N-terminus of the BP26;
- and
- wherein the nanoarchitecture comprises 8 or 16 copies of the fusion protein.
Dependencies are inferred from the claim text.