Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
AssigneeCompass Pathfinder Limited
InventorsDerek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, David E. Nichols
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Abstract
This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
Claims24
Crystalline psilocybin characterized by X-ray powder diffraction (XRPD) peaks at 17.5±0.1 and 19.7±0.1 °2θ, wherein the crystalline psilocybin is stable for at least 3 months at 25° C. and 60% relative humidity.
Crystalline psilocybin characterized by X-ray powder diffraction (XRPD) peaks at 17.5±0.1 and 19.7±0.1 °2θ, wherein the crystalline psilocybin is stable for at least 3 months at 40° C. and 75% relative humidity.
Dependencies are inferred from the claim text.