Nucleic acid extraction device

A nucleic acid extraction device, comprising:

• a driving component, a piston, a turntable, a plurality of chambers, a permanent magnet, and a plurality of magnetic beads;
• wherein the driving component is configured to carry and drive components of the nucleic acid extraction device to work, the driving component comprises a piston driving mechanism and a worm gear and worm transmission mechanism, the worm gear and worm transmission mechanism comprises a worm, a worm shaft, a worm gear, an elastic element, and a connecting module;
• the piston driving mechanism is configured to drive the piston of the nucleic acid extraction device to move vertically;
• the worm gear and worm transmission mechanism is configured to drive the turntable to rotate, thereby connecting or disconnecting the plurality of chambers of the nucleic acid extraction device;
• and the worm gear and worm transmission mechanism is provided with the elastic element capable of resetting, which is configured to provide thrust to the worm shaft to make the worm close to the worm gear so as to eliminate a backlash,
• wherein the plurality of chambers comprises a reaction chamber, the piston is configured to control a flow direction of a fluid;
• the reaction chamber is configured to provide a place for the magnetic beads to adsorb, wash and elute nucleic acids;
• the permanent magnet is configured to provide a magnetic attraction force for the magnetic beads;
• the permanent magnet is a magnetic rod;
• and the piston is located inside or outside the reaction chamber;
• wherein when the piston is located inside the reaction chamber, the reaction chamber is internally provided with the piston and a hollow accommodating chamber;
• the hollow accommodating chamber is configured to accommodate the permanent magnet, the piston is a hollow cylinder, and the hollow cylinder in the piston has the diameter matching that of the hollow accommodating chamber, so that the piston can be sleeved outside the hollow accommodating chamber and move vertically along an outer wall of the hollow accommodating chamber;
• and the displacement of the piston causes the pressure change, thereby promoting the fluids to flow between the reaction chamber and other chambers.

The nucleic acid extraction device, comprising:

• a driving component, a piston, a turntable, a plurality of chambers, a permanent magnet, and a plurality of magnetic beads;
• wherein the driving component is configured to carry and drive components of the nucleic acid extraction device to work, the driving component comprises a piston driving mechanism and a worm gear and worm transmission mechanism, the worm gear and worm transmission mechanism comprises a worm, a worm shaft, a worm gear, an elastic element, and a connecting module;
• the piston driving mechanism is configured to drive the piston of the nucleic acid extraction device to move vertically;
• the worm gear and worm transmission mechanism is configured to drive the turntable to rotate, thereby connecting or disconnecting the plurality of chambers of the nucleic acid extraction device;
• and the worm gear and worm transmission mechanism is provided with the elastic element capable of resetting, which is configured to provide thrust to the worm shaft to make the worm close to the worm gear so as to eliminate a backlash,
• wherein the plurality of chambers comprises a reaction chamber, the piston is configured to control a flow direction of a fluid;
• the reaction chamber is configured to provide a place for the magnetic beads to adsorb, wash and elute nucleic acids;
• the permanent magnet is configured to provide a magnetic attraction force for the magnetic beads;
• the permanent magnet is a magnetic rod;
• and the piston is located inside or outside the reaction chamber;
• wherein when the piston is located outside the reaction chamber, the permanent magnet and the piston are separately arranged;
• the piston is located above the reaction chamber;
• the permanent magnet is located below the reaction chamber;
• and the permanent magnet is the vertically placed magnetic rod, and the piston, the reaction chamber and the magnetic rod are arranged vertically in sequence from top to bottom.